A rash caused by poison ivy, oak, or sumac may itch and produce blisters. The form of Benadryl you spread on your skin may cause another allergic reaction. Exposure to poison ivy, poison oak, and p. diphenhydramine [sample brand name Benadryl]) can help you to ignore the itch while sleeping. Only humans are susceptible to the poison ivy rash. and diphenhydramine ( Benadryl) can help ease your itching and inflammation, too.
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